Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 11/20 | 0.61 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.56 |
| ▸ | HTR6 | P50406 | 2/20 | 0.55 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.48 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.48 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16727061 | 0.91 | AKR1C3 (0.57) | AKR1C3AKR1C2HTR6MTNR1AL3MBTL1 | |
| SCHEMBL16727064 | 0.90 | AKR1C3 (0.56) | AKR1C3AKR1C2HTR6MTNR1AL3MBTL1 | |
| SCHEMBL29169601 | 0.89 | HTR6 (0.57) | AKR1C3AKR1C2HTR6MTNR1AL3MBTL1 | |
| SCHEMBL24723630 | 0.88 | AKR1C3 (0.54) | AKR1C3AKR1C2HTR6MTNR1AL3MBTL1 | |
| SCHEMBL2724803 | 0.87 | AKR1C3 (0.53) | AKR1C3AKR1C2HTR6MTNR1AL3MBTL1 | |
| SCHEMBL29993260 | 0.86 | AKR1C3 (0.58) | AKR1C3AKR1C2HTR6MTNR1AL3MBTL1 | |
| SCHEMBL24877860 | 0.86 | HTR6 (0.76) | AKR1C3HTR6MTNR1A | |
| SCHEMBL30485883 | 0.86 | HTR6 (0.76) | AKR1C3HTR6MTNR1A | |
| SCHEMBL24723812 | 0.86 | AKR1C3 (0.57) | AKR1C3AKR1C2HTR6MTNR1AL3MBTL1 | |
| SCHEMBL29992497 | 0.86 | AKR1C3 (0.57) | AKR1C3AKR1C2HTR6MTNR1AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008014249-A2 | IMPROVED PREPARATIONS OF 2 -SUBSTITUTED PYRROLO [2, 3-B] PYRAZINE ( 4, 7 -DIAZAINDOLE ) COMPOUNDS | SANOFI-AVENTIS (FR) | 2008-01-31 | — | — | WO | disclosed |