Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 7/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5017752 | 0.82 | HCRTR2 (0.45) | HCRTR2HCRTR1ALDH1A1MEN1KMT2A | |
| SCHEMBL5023886 | 0.82 | HCRTR2 (0.45) | HCRTR2HCRTR1ALDH1A1MEN1KMT2A | |
| SCHEMBL5017748 | 0.82 | HCRTR2 (0.45) | HCRTR2HCRTR1ALDH1A1MEN1KMT2A | |
| SCHEMBL6449877 | 0.77 | HCRTR2 (0.53) | HCRTR2HCRTR1ALDH1A1MEN1KMT2A | |
| SCHEMBL3677750 | 0.77 | HCRTR2 (0.53) | HCRTR2HCRTR1ALDH1A1MEN1KMT2A | |
| SCHEMBL7504824 | 0.77 | HCRTR2 (0.53) | HCRTR2HCRTR1ALDH1A1MEN1KMT2A | |
| SCHEMBL14285582 | 0.77 | HCRTR2 (0.41) | HCRTR2HCRTR1MEN1KMT2ATDP1 | |
| SCHEMBL14285579 | 0.77 | HCRTR2 (0.41) | HCRTR2HCRTR1MEN1KMT2ATDP1 | |
| SCHEMBL5023922 | 0.76 | HCRTR1 (0.51) | HCRTR2HCRTR1MEN1KMT2ATDP1 | |
| SCHEMBL5023915 | 0.76 | HCRTR1 (0.51) | HCRTR2HCRTR1MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7314940-B2 | For therapy and prophylaxis of neurodegenerative disorders related to apoptosis and/or inflammation | EISAI CO., LTD. (JP) | 2008-01-01 | — | — | US | disclosed |