Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 18/20 | 0.51 |
| ▸ | HCRTR2 | O43614 | 18/20 | 0.51 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5023922 | 1.00 | HCRTR1 (0.51) | HCRTR1HCRTR2TRPV6MEN1KMT2A | |
| SCHEMBL5023886 | 0.94 | HCRTR2 (0.45) | HCRTR1HCRTR2TRPV6MEN1KMT2A | |
| SCHEMBL5017752 | 0.94 | HCRTR2 (0.45) | HCRTR1HCRTR2TRPV6MEN1KMT2A | |
| SCHEMBL5017748 | 0.94 | HCRTR2 (0.45) | HCRTR1HCRTR2TRPV6MEN1KMT2A | |
| SCHEMBL14285587 | 0.83 | HCRTR1 (0.47) | HCRTR1HCRTR2 | |
| SCHEMBL25235970 | 0.79 | HCRTR1 (0.51) | HCRTR1HCRTR2 | |
| SCHEMBL14309091 | 0.76 | HCRTR2 (0.45) | HCRTR1HCRTR2MEN1KMT2ATDP1 | |
| SCHEMBL4574026 | 0.76 | HCRTR1 (0.57) | HCRTR1HCRTR2 | |
| SCHEMBL4574022 | 0.76 | HCRTR1 (0.57) | HCRTR1HCRTR2 | |
| SCHEMBL14285579 | 0.75 | HCRTR2 (0.41) | HCRTR1HCRTR2MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7314940-B2 | For therapy and prophylaxis of neurodegenerative disorders related to apoptosis and/or inflammation | EISAI CO., LTD. (JP) | 2008-01-01 | — | — | US | disclosed |
| US-7314940-B2 | For therapy and prophylaxis of neurodegenerative disorders related to apoptosis and/or inflammation | EISAI CO., LTD. (JP) | 2008-01-01 | — | — | US | disclosed |