Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 6/20 | 0.43 |
| ▸ | CA2 | P00918 | 6/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13405019 | 0.89 | MEN1 (0.54) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL16286191 | 0.85 | MEN1 (0.59) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL10190369 | 0.83 | TDP1 (0.59) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL8062203 | 0.83 | TDP1 (0.59) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL20358461 | 0.83 | MEN1 (0.56) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL23168272 | 0.83 | TDP1 (0.59) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL22162664 | 0.82 | MEN1 (0.55) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL3082046 | 0.82 | MEN1 (0.55) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL3082048 | 0.82 | MEN1 (0.55) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL13767609 | 0.82 | MEN1 (0.55) | MEN1KMT2AGAATDP1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7314940-B2 | For therapy and prophylaxis of neurodegenerative disorders related to apoptosis and/or inflammation | EISAI CO., LTD. (JP) | 2008-01-01 | — | — | US | disclosed |