Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 7/20 | 0.46 |
| ▸ | CA2 | P00918 | 7/20 | 0.46 |
| ▸ | CA12 | O43570 | 6/20 | 0.46 |
| ▸ | CA9 | Q16790 | 6/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 3/20 | 0.39 |
| ▸ | CTSS | P25774 | 2/20 | 0.39 |
| ▸ | STK17B | O94768 | 1/20 | 0.39 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13405019 | 0.96 | MEN1 (0.54) | MEN1KMT2AGAATDP1CA1 | |
| SCHEMBL16285824 | 0.91 | MEN1 (0.50) | MEN1KMT2AGAATDP1CA1 | |
| SCHEMBL6244166 | 0.85 | MEN1 (0.62) | MEN1KMT2AGAATDP1CA1 | |
| SCHEMBL12666362 | 0.85 | MEN1 (0.62) | MEN1KMT2AGAATDP1CA1 | |
| SCHEMBL19301024 | 0.85 | MEN1 (0.62) | MEN1KMT2AGAATDP1CA1 | |
| SCHEMBL24075383 | 0.85 | TDP1 (0.45) | MEN1KMT2AGAATDP1CA1 | |
| SCHEMBL24075378 | 0.85 | SYK (0.41) | MEN1KMT2AGAACA1CA2 | |
| SCHEMBL7730493 | 0.85 | MEN1 (0.62) | MEN1KMT2AGAATDP1CA1 | |
| SCHEMBL14309092 | 0.85 | MEN1 (0.51) | MEN1KMT2AGAATDP1CA1 | |
| SCHEMBL13405015 | 0.84 | TDP1 (0.47) | MEN1KMT2AGAATDP1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9371274-B2 | Compound having read-through activity | THE UNIVERSITY OF TOKYO (JP) | 2016-06-21 | — | — | US | disclosed |
| US-20140364642-A1 | COMPOUND HAVING READ-THROUGH ACTIVITY | THE UNIVERSITY OF TOKYO (JP) | 2014-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140364642-A1 | COMPOUND HAVING READ-THROUGH ACTIVITY | UPF1, NUDT21, GBA2 | MEN1 1290/4885KMT2A 2365/4885GAA 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.