Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25784833 | 0.79 | EGLN3 (0.41) | EGLN3TLR8TLR7MEN1KMT2A | |
| SCHEMBL2535061 | 0.78 | EGLN3 (0.54) | EGLN3MEN1KMT2AMAPTLMNA | |
| Hydrochloric Acid SCHEMBL2530861 | 0.76 | EGLN3 (0.52) | EGLN3MEN1KMT2AMAPTLMNA | |
| SCHEMBL11471409 | 0.73 | TBXAS1 (0.46) | EGLN3TLR8TLR7MEN1KMT2A | |
| SCHEMBL11485316 | 0.73 | TBXAS1 (0.46) | EGLN3TLR8TLR7MEN1KMT2A | |
| SCHEMBL23609758 | 0.73 | EGLN3 (0.46) | EGLN3TLR8TLR7MEN1KMT2A | |
| SCHEMBL11471431 | 0.73 | TBXAS1 (0.46) | EGLN3TLR8TLR7MEN1KMT2A | |
| SCHEMBL11488575 | 0.73 | TBXAS1 (0.46) | EGLN3TLR8TLR7MEN1KMT2A | |
| SCHEMBL11479603 | 0.73 | TBXAS1 (0.46) | EGLN3TLR8TLR7MEN1KMT2A | |
| SCHEMBL11471344 | 0.73 | TBXAS1 (0.46) | EGLN3TLR8TLR7MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021195346-A1 | LIPOXYGENASE INHIBITORS | SRI INTERNATIONAL (US) | 2021-09-30 | — | — | WO | disclosed |
| WO-2021133689-A2 | LIPOXYGENASE INHIBITORS | SRI INTERNATIONAL (US) | 2021-07-01 | — | — | WO | disclosed |
| EP-1878733-A1 | Pyrimidine derivatives as ALK-5 inhibitors | Novartis AG (CH) | 2008-01-16 | — | — | EP | disclosed |