Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGPL1 | O95470 | 3/20 | 0.42 |
| ▸ | CXCR3 | P49682 | 7/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | SMO | Q99835 | 2/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4395236 | 0.90 | CXCR3 (0.38) | SGPL1CXCR3SMODYRK1ALMNA | |
| SCHEMBL4395233 | 0.90 | CXCR3 (0.38) | SGPL1CXCR3SMODYRK1ALMNA | |
| SCHEMBL4250881 | 0.90 | CXCR3 (0.39) | SGPL1CXCR3RETSMODYRK1A | |
| SCHEMBL4250878 | 0.90 | CXCR3 (0.39) | SGPL1CXCR3RETSMODYRK1A | |
| SCHEMBL4246983 | 0.89 | CXCR3 (0.38) | SGPL1CXCR3RETSMODYRK1A | |
| SCHEMBL4253832 | 0.89 | CXCR3 (0.38) | SGPL1CXCR3RETSMODYRK1A | |
| SCHEMBL4246977 | 0.89 | CXCR3 (0.38) | SGPL1CXCR3RETSMODYRK1A | |
| SCHEMBL4249522 | 0.89 | CXCR3 (0.38) | SGPL1CXCR3RETSMODYRK1A | |
| SCHEMBL4251539 | 0.88 | SGPL1 (0.40) | SGPL1CXCR3RETSMOLMNA | |
| SCHEMBL4251536 | 0.88 | SGPL1 (0.40) | SGPL1CXCR3RETSMOLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008011611-A2 | COMPOUNDS AND COMPOSITIONS AS ITPKB INHIBITORS | IRM LLC (BM) | 2008-01-24 | — | — | WO | disclosed |