Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 10/20 | 0.64 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | ADK | P55263 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | ATP4A | P20648 | 2/20 | 0.34 |
| ▸ | ATP4B | P51164 | 2/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3732212 | 0.80 | PIK3CG (0.54) | PIK3CGJAK3ADKPOLB | |
| SCHEMBL3533560 | 0.78 | PIK3CG (1.00) | PIK3CGJAK3ADKPIK3CDPIK3CB | |
| Hydrochloric Acid SCHEMBL3536157 | 0.77 | PIK3CG (0.97) | PIK3CGJAK3ADKPIK3CDPIK3CB | |
| SCHEMBL3732209 | 0.76 | PIK3CG (0.82) | PIK3CGJAK3ADKPIK3CDPIK3CB | |
| SCHEMBL13043249 | 0.75 | PIK3CG (0.85) | PIK3CGJAK3ADKATP4AATP4B | |
| SCHEMBL13927979 | 0.74 | PIK3CG (0.89) | PIK3CGJAK3ADKPIK3CDPIK3CB | |
| SCHEMBL14983470 | 0.69 | POLB (0.56) | PIK3CGAPPIDO1PIK3CDPIK3CB | |
| SCHEMBL3745443 | 0.68 | PIK3CG (0.70) | PIK3CGJAK3ADKPIK3CDPIK3CB | |
| SCHEMBL3745440 | 0.68 | PIK3CG (0.70) | PIK3CGADKPIK3CDPIK3CB | |
| SCHEMBL3536162 | 0.68 | PIK3CG (0.75) | PIK3CGJAK3ADKPIK3CDPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2039683-B1 | Vasculostatic agents and methods of use thereof | TARGEGEN INC (US) | 2012-12-19 | — | — | EP | disclosed |