Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 14/20 | 0.85 |
| ▸ | PIK3CD | O00329 | 6/20 | 0.51 |
| ▸ | ABL1 | P00519 | 5/20 | 0.51 |
| ▸ | EGFR | P00533 | 5/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.51 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.51 |
| ▸ | MTOR | P42345 | 5/20 | 0.51 |
| ▸ | PI4KB | Q9UBF8 | 5/20 | 0.51 |
| ▸ | HCK | P08631 | 4/20 | 0.51 |
| ▸ | SRC | P12931 | 4/20 | 0.51 |
| ▸ | KDR | P35968 | 4/20 | 0.51 |
| ▸ | EPHB4 | P54760 | 4/20 | 0.51 |
| ▸ | PRKDC | P78527 | 4/20 | 0.51 |
| ▸ | ADK | P55263 | 1/20 | 0.49 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | JAK3 | P52333 | 1/20 | 0.42 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.39 |
| ▸ | PDXK | O00764 | 1/20 | 0.39 |
| ▸ | GAK | O14976 | 1/20 | 0.39 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3533560 | 0.92 | PIK3CG (1.00) | PIK3CGPIK3CDABL1EGFRPIK3CA | |
| Hydrochloric Acid SCHEMBL3536157 | 0.91 | PIK3CG (0.97) | PIK3CGPIK3CDABL1EGFRPIK3CA | |
| SCHEMBL13927979 | 0.87 | PIK3CG (0.89) | PIK3CGPIK3CDABL1EGFRPIK3CA | |
| SCHEMBL3732209 | 0.86 | PIK3CG (0.82) | PIK3CGPIK3CDABL1EGFRPIK3CA | |
| SCHEMBL13043247 | 0.83 | PIK3CG (0.84) | PIK3CGPIK3CDABL1EGFRPIK3CA | |
| SCHEMBL3536162 | 0.80 | PIK3CG (0.75) | PIK3CGPIK3CDABL1EGFRPIK3CA | |
| SCHEMBL3745443 | 0.79 | PIK3CG (0.70) | PIK3CGPIK3CDABL1EGFRPIK3CA | |
| SCHEMBL3745440 | 0.79 | PIK3CG (0.70) | PIK3CGPIK3CDABL1EGFRPIK3CA | |
| SCHEMBL3532692 | 0.76 | PIK3CG (1.00) | PIK3CGPIK3CDABL1EGFRPIK3CA | |
| SCHEMBL13019024 | 0.76 | PIK3CG (0.86) | PIK3CGPIK3CDABL1EGFRPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100278811-A1 | VASCULOSTATIC AGENTS AND METHODS OF USE THEREOF | TARGEGEN INC. | 2010-11-04 | — | — | US | disclosed |
| US-20070208019-A1 | Vasculostatic agents and methods of use thereof | TARGEGEN, INC. | 2007-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070208019-A1 | Vasculostatic agents and methods of use thereof | RBP1, RBP4, VCAM1 | PIK3CG 2378/4885PIK3CD 3513/4885ABL1 4387/4885 |
| US-20100278811-A1 | VASCULOSTATIC AGENTS AND METHODS OF USE THEREOF | RBP1, RBP4, VCAM1 | PIK3CG 2378/4885PIK3CD 3513/4885ABL1 4387/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.