Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 7/20 | 0.50 |
| ▸ | CCR3 | P51677 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3950707 | 0.85 | CETP (0.44) | CETPCCR3MMP13MEN1KMT2A | |
| SCHEMBL14319916 | 0.82 | CHRM2 (0.47) | CETPCHRM2CHRM1CHRM3 | |
| SCHEMBL14311123 | 0.81 | CETP (0.50) | CETPKDM1ADPP4 | |
| SCHEMBL13608939 | 0.80 | CETP (0.60) | CETP | |
| SCHEMBL14309731 | 0.80 | CETP (0.60) | CETP | |
| SCHEMBL3943995 | 0.80 | CETP (0.60) | CETP | |
| SCHEMBL13608938 | 0.80 | CETP (0.60) | CETP | |
| SCHEMBL3942600 | 0.78 | CETP (0.58) | CETP | |
| SCHEMBL13609119 | 0.78 | CETP (0.58) | CETP | |
| SCHEMBL14668817 | 0.76 | CHRM2 (0.44) | CETPCHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008009435-A1 | AMINO-PIPERIDINE DERIVATIVES AS CETP INHIBITORS | NOVARTIS AG (CH) | 2008-01-24 | — | — | WO | disclosed |