Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.72 |
| ▸ | HTT | P42858 | 3/20 | 0.72 |
| ▸ | CCR9 | P51686 | 7/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | BDKRB1 | P46663 | 4/20 | 0.54 |
| ▸ | SLC10A6 | Q3KNW5 | 1/20 | 0.54 |
| ▸ | CCR2 | P41597 | 1/20 | 0.53 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28006 | 0.88 | LMNA (0.86) | LMNAHTTCCR9MAPTTP53 | |
| SCHEMBL27979 | 0.87 | LMNA (0.83) | LMNAHTTCCR9MAPTTP53 | |
| SCHEMBL12242366 | 0.85 | LMNA (0.80) | LMNAHTTCCR9MAPTTP53 | |
| SCHEMBL13137558 | 0.85 | LMNA (0.80) | LMNAHTTCCR9MAPTTP53 | |
| SCHEMBL28518 | 0.85 | LMNA (0.80) | LMNAHTTCCR9MAPTTP53 | |
| SCHEMBL28625 | 0.84 | BDKRB1 (0.76) | LMNAHTTCCR9MAPTTP53 | |
| SCHEMBL11182634 | 0.84 | LMNA (1.00) | LMNAHTTCCR9MAPTTP53 | |
| SCHEMBL27758 | 0.84 | LMNA (0.78) | LMNAHTTCCR9MAPTTP53 | |
| SCHEMBL2531519 | 0.84 | LMNA (0.82) | LMNAHTTCCR9MAPTTP53 | |
| SCHEMBL28469 | 0.84 | CCR9 (0.79) | LMNAHTTCCR9MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567486-B1 | BIS-ARYL SULFONAMIDES | CHEMOCENTRYX INC (US) | 2008-01-16 | — | — | EP | disclosed |