Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN7A | Q01118 | 2/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.48 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.48 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.48 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18117312 | 0.99 | SCN7A (0.53) | SCN7AHTR7SCN5ASCN2ASCN8A | |
| SCHEMBL706822 | 0.85 | KCNH2 (0.43) | SCN7AHTR7DRD2 | |
| Hydrochloric Acid SCHEMBL3870194 | 0.84 | KCNH2 (0.43) | SCN7AHTR7DRD2 | |
| SCHEMBL4294672 | 0.82 | HTR7 (0.38) | SCN7AHTR7SCN5ASCN2ASCN8A | |
| SCHEMBL921593 | 0.79 | CNR2 (0.46) | MCHR1 | |
| SCHEMBL31033172 | 0.79 | SCN7A (0.56) | SCN7ASCN5ASCN2ASCN8A | |
| SCHEMBL3861905 | 0.79 | BPTF (0.41) | HTR7GRIN1GRIN2BDRD2MCHR1 | |
| SCHEMBL30448661 | 0.78 | HDAC1 (0.43) | PLK1 | |
| SCHEMBL28779597 | 0.78 | HDAC1 (0.43) | HTR7PLK1DRD2 | |
| SCHEMBL14020817 | 0.78 | KCNH2 (0.58) | GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008009700-A1 | DERIVATIVES AND ANALOGS OF N-ETHYLQUINOLONES AND N-ETHYLAZAQUINOLONES | GLAXO GROUP LIMITED (GB) | 2008-01-24 | — | — | WO | disclosed |