Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.46 |
| ▸ | CDK4 | P11802 | 3/20 | 0.45 |
| ▸ | CCND1 | P24385 | 3/20 | 0.45 |
| ▸ | CCND2 | P30279 | 3/20 | 0.45 |
| ▸ | CCND3 | P30281 | 3/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28779597 | 0.86 | HDAC1 (0.43) | CDK4CCND1CCND2CCND3HDAC1 | |
| SCHEMBL17637279 | 0.83 | HDAC1 (0.45) | BTKCDK4CCND1CCND2CCND3 | |
| SCHEMBL6333356 | 0.80 | BTK (0.57) | BTKCDK4CCND1CCND2CCND3 | |
| SCHEMBL3839835 | 0.79 | HDAC1 (0.43) | CDK4CCND1CCND2CCND3HDAC1 | |
| SCHEMBL30448661 | 0.79 | HDAC1 (0.43) | BTKHDAC1HDAC6HTR2CHTR2A | |
| SCHEMBL20338313 | 0.79 | MAPT (0.40) | CDK4CCND1CCND2CCND3MAPT | |
| SCHEMBL30355117 | 0.79 | BTK (0.46) | BTKCDK4CCND1CCND2CCND3 | |
| SCHEMBL3862000 | 0.78 | HDAC1 (0.42) | HDAC1HDAC6MAPTSMN1; SMN2HTR2C | |
| Hydrochloric Acid SCHEMBL17581004 | 0.78 | HDAC1 (0.42) | HDAC1HDAC6HTR2CHTR2APLK1 | |
| SCHEMBL17580899 | 0.78 | PTGDR2 (0.45) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160090383-A1 | ANTIBACTERIAL PHTHALIDE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2016-03-31 | — | — | US | disclosed |
| WO-2008009700-A1 | DERIVATIVES AND ANALOGS OF N-ETHYLQUINOLONES AND N-ETHYLAZAQUINOLONES | GLAXO GROUP LIMITED (GB) | 2008-01-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160090383-A1 | ANTIBACTERIAL PHTHALIDE DERIVATIVES | MRPL21, MAPRE1, HDAC6 | BTK 3039/4885CDK4 3531/4885CCND1 2153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.