Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | XIAP | P98170 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MASP2 | O00187 | 2/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 2/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.36 |
| ▸ | PPIB | P23284 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1432074 | 1.00 | DPP4 (0.38) | DPP4KCNH2MEN1KMT2AXIAP | |
| SCHEMBL1431769 | 0.94 | DPP4 (0.39) | DPP4KCNH2MEN1KMT2AXIAP | |
| SCHEMBL1432630 | 0.94 | DPP4 (0.39) | DPP4KCNH2MEN1KMT2AXIAP | |
| SCHEMBL1432146 | 0.92 | MEN1 (0.46) | MEN1KMT2AALDH1A1LMNAMASP2 | |
| SCHEMBL1432209 | 0.91 | F2 (0.42) | DPP4KCNH2MEN1KMT2AXIAP | |
| SCHEMBL1432780 | 0.91 | F2 (0.42) | DPP4KCNH2MEN1KMT2AXIAP | |
| SCHEMBL1431638 | 0.90 | DPP4 (0.40) | DPP4KCNH2MEN1KMT2AXIAP | |
| SCHEMBL1432180 | 0.90 | DPP4 (0.40) | DPP4KCNH2MEN1KMT2AXIAP | |
| SCHEMBL3150073 | 0.90 | MASP2 (0.40) | DPP4KCNH2MEN1KMT2AXIAP | |
| Hydrochloric Acid SCHEMBL1432515 | 0.90 | DPP4 (0.40) | DPP4KCNH2MEN1KMT2AXIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | claimed |