Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MASP2 | O00187 | 3/20 | 0.51 |
| ▸ | KLKB1 | P03952 | 9/20 | 0.49 |
| ▸ | MMP8 | P22894 | 2/20 | 0.47 |
| ▸ | MME | P08473 | 2/20 | 0.46 |
| ▸ | ACE | P12821 | 2/20 | 0.46 |
| ▸ | CPA1 | P15085 | 2/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.46 |
| ▸ | MMP1 | P03956 | 2/20 | 0.45 |
| ▸ | FCER2 | P06734 | 2/20 | 0.45 |
| ▸ | KLK1 | P06870 | 2/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1431962 | 0.92 | ACE (0.47) | MASP2KLKB1MMEACECPA1 | |
| SCHEMBL1432331 | 0.91 | MASP2 (0.44) | MASP2KLKB1KLK1 | |
| SCHEMBL1432584 | 0.91 | MME (0.44) | MASP2KLKB1MMEACECPA1 | |
| SCHEMBL1432156 | 0.90 | MASP2 (0.45) | MASP2KLKB1 | |
| SCHEMBL1432540 | 0.89 | MASP2 (0.43) | MASP2KLKB1KLK1 | |
| SCHEMBL1431493 | 0.89 | MASP2 (0.46) | MASP2KLKB1MMEACECPA1 | |
| SCHEMBL1431833 | 0.88 | MASP2 (0.45) | MASP2KLKB1KLK1 | |
| SCHEMBL1431873 | 0.87 | MASP2 (0.42) | MASP2KLKB1MMEACECPA1 | |
| SCHEMBL1431845 | 0.87 | MME (0.51) | MASP2KLKB1MMP8MMEACE | |
| SCHEMBL1431687 | 0.87 | MME (0.44) | MASP2KLKB1MMEACECPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |