Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 15/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1431740 | 0.93 | F2 (0.46) | F2 | |
| SCHEMBL1432354 | 0.88 | HDAC8 (0.45) | F2PRSS1KLKB1 | |
| SCHEMBL3154741 | 0.85 | F2 (0.58) | F2KLKB1 | |
| SCHEMBL3149590 | 0.85 | F2 (0.58) | F2KLKB1 | |
| SCHEMBL1432496 | 0.84 | F2 (0.44) | F2PRSS1 | |
| SCHEMBL1431488 | 0.84 | MALT1 (0.39) | — | |
| SCHEMBL1431804 | 0.83 | F2 (0.43) | F2PRSS1KLKB1 | |
| SCHEMBL1432357 | 0.82 | F2 (0.53) | F2PRSS1 | |
| SCHEMBL3148675 | 0.82 | F2 (0.53) | F2PRSS1 | |
| SCHEMBL1431704 | 0.78 | MASP2 (0.43) | KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |
| WO-2009133348-A1 | AMINOPYRIDINE DERIVATIVES | VANTIA LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |