Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MASP2 | O00187 | 3/20 | 0.39 |
| ▸ | PPIB | P23284 | 1/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.36 |
| ▸ | ITGAV | P06756 | 1/20 | 0.36 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | FURIN | P09958 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1432690 | 1.00 | TLR2 (0.42) | TLR2MEN1KMT2AMASP2PPIB | |
| SCHEMBL1431814 | 0.93 | MEN1 (0.48) | TLR2MEN1KMT2AMASP2PPIB | |
| SCHEMBL1432532 | 0.93 | MEN1 (0.48) | TLR2MEN1KMT2AMASP2PPIB | |
| SCHEMBL1433055 | 0.93 | KMT2A (0.43) | TLR2MEN1KMT2AMASP2PPIB | |
| SCHEMBL1432319 | 0.93 | KMT2A (0.43) | TLR2MEN1KMT2AMASP2PPIB | |
| SCHEMBL1432180 | 0.92 | DPP4 (0.40) | TLR2MEN1KMT2AMASP2PPIB | |
| SCHEMBL1431638 | 0.92 | DPP4 (0.40) | TLR2MEN1KMT2AMASP2PPIB | |
| Hydrochloric Acid SCHEMBL1432515 | 0.91 | DPP4 (0.40) | TLR2MEN1KMT2AMASP2PPIB | |
| SCHEMBL1433193 | 0.91 | MEN1 (0.47) | TLR2MEN1KMT2AMASP2PPIB | |
| SCHEMBL1432347 | 0.91 | MEN1 (0.47) | TLR2MEN1KMT2AMASP2PPIB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | claimed |