Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.40 |
| ▸ | MASP2 | O00187 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
| ▸ | XIAP | P98170 | 2/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | PPIB | P23284 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1432319 | 1.00 | KMT2A (0.43) | KMT2AMEN1CCNT1TACR1AADAT | |
| SCHEMBL1432452 | 0.93 | TLR2 (0.42) | KMT2AMEN1CCNT1TACR1AADAT | |
| SCHEMBL1432690 | 0.93 | TLR2 (0.42) | KMT2AMEN1CCNT1TACR1AADAT | |
| SCHEMBL1432803 | 0.91 | CTSB (0.41) | KMT2AMEN1MASP2ALDH1A1KLKB1 | |
| SCHEMBL1431638 | 0.91 | DPP4 (0.40) | KMT2AMEN1MASP2ALDH1A1LMNA | |
| SCHEMBL1432180 | 0.91 | DPP4 (0.40) | KMT2AMEN1MASP2ALDH1A1LMNA | |
| SCHEMBL1432532 | 0.91 | MEN1 (0.48) | KMT2AMEN1TACR1AADATMASP2 | |
| SCHEMBL1431814 | 0.91 | MEN1 (0.48) | KMT2AMEN1TACR1AADATMASP2 | |
| SCHEMBL1432409 | 0.90 | CTSL (0.48) | CTSSCTSK | |
| Hydrochloric Acid SCHEMBL1432515 | 0.90 | DPP4 (0.40) | KMT2AMEN1MASP2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |