Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 9/20 | 0.46 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22543799 | 0.85 | HSD17B10 (0.39) | HMGCRSQORHSD17B10 | |
| SCHEMBL24966591 | 0.77 | HSP90AA1 (0.41) | SQORHSD17B10 | |
| SCHEMBL25928607 | 0.72 | KDM4E (0.38) | HMGCRSQORHSD17B10 | |
| SCHEMBL19254164 | 0.71 | HMGCR (0.38) | HMGCR | |
| SCHEMBL22549257 | 0.71 | HSD17B10 (0.41) | SQORHSD17B10 | |
| SCHEMBL24848200 | 0.71 | HRH4 (0.35) | SQORHSD17B10 | |
| SCHEMBL18532051 | 0.71 | HMGCR (0.38) | HMGCR | |
| SCHEMBL18415080 | 0.71 | LOXL2 (0.34) | RIPK1 | |
| SCHEMBL12473918 | 0.69 | BACE1 (0.47) | — | |
| SCHEMBL18879383 | 0.69 | HSP90AA1 (0.39) | HMGCRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2537875-A1 | NOVEL POLYAZOMETHINE | Soken Chemical & Engineering Co., Ltd. (JP) | 2012-12-26 | — | — | EP | disclosed |