Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 5/20 | 0.36 |
| ▸ | CKS1B | P61024 | 6/20 | 0.36 |
| ▸ | SKP2 | Q13309 | 6/20 | 0.36 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.36 |
| ▸ | COMT | P21964 | 1/20 | 0.34 |
| ▸ | PIK3R2 | O00459 | 2/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 2/20 | 0.33 |
| ▸ | CCR5 | P51681 | 2/20 | 0.33 |
| ▸ | CCR8 | P51685 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14330534 | 0.84 | TOP1 (0.34) | TOP1CKS1BSKP2GLO1COMT | |
| SCHEMBL14329582 | 0.83 | CYP3A4 (0.40) | CCR1CCR5CCR8L3MBTL1KDM4E | |
| SCHEMBL14330496 | 0.83 | CYP17A1 (0.33) | TOP1CKS1BSKP2GLO1PIK3R2 | |
| SCHEMBL14330505 | 0.82 | TOP1 (0.35) | TOP1CKS1BSKP2GLO1COMT | |
| SCHEMBL14330502 | 0.82 | TNKS (0.32) | CKS1BSKP2GLO1CYP3A4 | |
| SCHEMBL14329607 | 0.82 | CYP1A2 (0.39) | CCR1CCR5CCR8L3MBTL1KDM4E | |
| SCHEMBL14329591 | 0.82 | KDM4E (0.39) | COMTCCR1CCR5CCR8L3MBTL1 | |
| SCHEMBL14330492 | 0.81 | KDM4E (0.35) | TOP1CKS1BSKP2GLO1COMT | |
| SCHEMBL14330504 | 0.81 | ALDH1A1 (0.33) | TOP1CKS1BSKP2GLO1L3MBTL1 | |
| SCHEMBL14331584 | 0.81 | TOP1 (0.40) | TOP1CKS1BSKP2GLO1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8771844-B2 | Heterocyclic compound and organic light-emitting diode and flat display device including the heterocyclic compound | SAMSUNG DISPLAY CO., LTD. (KR) | 2014-07-08 | — | — | US | disclosed |
| US-8771844-B2 | Heterocyclic compound and organic light-emitting diode and flat display device including the heterocyclic compound | SAMSUNG DISPLAY CO., LTD. (KR) | 2014-07-08 | — | — | US | disclosed |
| US-20120326135-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DIODE AND FLAT DISPLAY DEVICE INCLUDING THE HETEROCYCLIC COMPOUND | SAMSUNG DISPLAY CO., LTD. (KR) | 2012-12-27 | — | — | US | disclosed |
| US-20120326135-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DIODE AND FLAT DISPLAY DEVICE INCLUDING THE HETEROCYCLIC COMPOUND | SAMSUNG DISPLAY CO., LTD. (KR) | 2012-12-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120326135-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DIODE AND FLAT DISPLAY DEVICE INCLUDING THE HETEROCYCLIC COMPOUND | DDT, DRD1, HTR3D | TOP1 2657/4885CKS1B 3737/4885SKP2 436/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.