Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | XIAP | P98170 | 1/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
| ▸ | MASP2 | O00187 | 2/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CCR4 | P51679 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1432028 | 0.94 | HDAC1 (0.40) | HDAC1HDAC2HDAC3F2MEN1 | |
| SCHEMBL1432334 | 0.94 | F2 (0.46) | HDAC1HDAC2HDAC3F2MEN1 | |
| SCHEMBL1432083 | 0.91 | TACR1 (0.47) | HDAC1HDAC2HDAC3F2XIAP | |
| SCHEMBL1432037 | 0.91 | TACR1 (0.47) | HDAC1HDAC2HDAC3F2XIAP | |
| SCHEMBL3150073 | 0.91 | MASP2 (0.40) | F2MEN1KMT2AXIAPMASP2 | |
| SCHEMBL1431769 | 0.90 | DPP4 (0.39) | F2MEN1KMT2AXIAPMASP2 | |
| SCHEMBL1432630 | 0.90 | DPP4 (0.39) | F2MEN1KMT2AXIAPMASP2 | |
| SCHEMBL1432209 | 0.89 | F2 (0.42) | F2MEN1KMT2AXIAPMASP2 | |
| SCHEMBL1432780 | 0.89 | F2 (0.42) | F2MEN1KMT2AXIAPMASP2 | |
| SCHEMBL1432074 | 0.88 | DPP4 (0.38) | F2MEN1KMT2AXIAPMASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |