Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 11/20 | 0.72 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.67 |
| ▸ | NPC1 | O15118 | 8/20 | 0.60 |
| ▸ | RAB9A | P51151 | 8/20 | 0.60 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19766696 | 0.87 | S1PR1 (0.78) | S1PR1S1PR3NPC1RAB9ATP53 | |
| SCHEMBL13416794 | 0.84 | S1PR1 (0.72) | S1PR1S1PR3NPC1RAB9ATP53 | |
| SCHEMBL13416797 | 0.84 | S1PR1 (1.00) | S1PR1S1PR3NPC1RAB9ATP53 | |
| SCHEMBL14331473 | 0.83 | S1PR1 (0.67) | S1PR1S1PR3NPC1RAB9ATP53 | |
| SCHEMBL19766695 | 0.82 | S1PR1 (0.70) | S1PR1S1PR3NPC1RAB9ATP53 | |
| SCHEMBL13417221 | 0.81 | S1PR1 (1.00) | S1PR1S1PR3NPC1RAB9ATP53 | |
| SCHEMBL13525832 | 0.78 | NPC1 (0.55) | S1PR1S1PR3NPC1RAB9ATP53 | |
| SCHEMBL13416795 | 0.76 | S1PR1 (1.00) | S1PR1S1PR3NPC1RAB9ATP53 | |
| SCHEMBL13416805 | 0.74 | S1PR1 (1.00) | S1PR1S1PR3NPC1RAB9ATP53 | |
| SCHEMBL5959967 | 0.74 | SMN1; SMN2 (0.85) | S1PR1S1PR3NPC1RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120329838-A1 | NOVEL MODULATORS OF SPHINGOSINE PHOSPHATE RECEPTORS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2012-12-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120329838-A1 | NOVEL MODULATORS OF SPHINGOSINE PHOSPHATE RECEPTORS | S1PR1, S1PR3, S1PR2 | S1PR1 1/4885S1PR3 2/4885NPC1 1349/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.