Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 2/20 | 0.57 |
| ▸ | CTSL | P07711 | 18/20 | 0.47 |
| ▸ | CTSS | P25774 | 17/20 | 0.47 |
| ▸ | CTSV | O60911 | 16/20 | 0.47 |
| ▸ | CTSK | P43235 | 12/20 | 0.47 |
| ▸ | CTSB | P07858 | 9/20 | 0.47 |
| ▸ | KLK1 | P06870 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1433580 | 0.90 | KLKB1 (0.65) | KLKB1KLK1 | |
| SCHEMBL1433325 | 0.90 | KLKB1 (0.57) | KLKB1CTSLCTSSCTSKCTSB | |
| SCHEMBL1432921 | 0.90 | KLKB1 (0.52) | KLKB1CTSBKLK1 | |
| SCHEMBL1432904 | 0.88 | KLKB1 (0.55) | KLKB1CTSLCTSSCTSVCTSK | |
| SCHEMBL1432988 | 0.88 | KLKB1 (0.52) | KLKB1CTSBKLK1 | |
| SCHEMBL1432955 | 0.88 | KLKB1 (0.54) | KLKB1CTSLCTSSKLK1 | |
| SCHEMBL1433012 | 0.88 | KLKB1 (0.57) | KLKB1CTSLCTSSKLK1 | |
| SCHEMBL1434866 | 0.87 | KLKB1 (0.53) | KLKB1CTSLCTSSCTSKKLK1 | |
| SCHEMBL1433064 | 0.87 | KLKB1 (0.61) | KLKB1CTSLCTSSCTSKCTSB | |
| SCHEMBL1433306 | 0.86 | KLKB1 (0.55) | KLKB1CTSLCTSSCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |