SCHEMBL14335757

SCHEMBL14335757

CCC(COc1ccccc1)OC(=O)c1cccc(Cl)c1

nearest known ligand 0.86

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.53
▸ LMNA P02545 1/20 0.53
▸ TSHR P16473 1/20 0.53
▸ ALOX12 P18054 1/20 0.53
▸ KMT2A Q03164 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14335193 0.90 LMNA (0.53) MEN1LMNATSHRALOX12KMT2A
SCHEMBL14334607 0.89 TDP1 (0.44) MEN1LMNATSHRALOX12KMT2A
SCHEMBL14335620 0.88 MEN1 (0.57) MEN1LMNATSHRALOX12KMT2A
SCHEMBL14335640 0.88 LMNA (0.48) MEN1LMNATSHRALOX12KMT2A
SCHEMBL14335371 0.86 NR4A2 (0.47) MEN1LMNATSHRALOX12KMT2A
SCHEMBL14334946 0.86 MEN1 (0.55) MEN1LMNATSHRALOX12KMT2A
SCHEMBL14335042 0.85 LMNA (0.47) MEN1LMNATSHRALOX12KMT2A
SCHEMBL14334871 0.84 HPGD (0.54) MEN1KMT2A
SCHEMBL14334771 0.83 HPGD (0.44) MEN1LMNAKMT2A
SCHEMBL14334768 0.83 LMNA (0.46) MEN1LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2723780-B1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA SRL (IT) 2017-04-26 — — EP disclosed
US-9034783-B2 Catalyst components for the polymerization of olefins BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2015-05-19 — — US disclosed
US-20140142262-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.I. (IT) 2014-05-22 — — US disclosed
EP-2723780-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.r.l. (IT) 2014-04-30 — — EP disclosed
WO-2012175425-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2012-12-27 — — WO disclosed
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