⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28595938 | 1.00 | — | — | |
| SCHEMBL29956680 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL25279878 | 0.98 | GRM4 (0.41) | — | |
| Hydrochloric Acid SCHEMBL28913901 | 0.98 | GRM4 (0.41) | — | |
| Hydrochloric Acid SCHEMBL28913902 | 0.98 | GRM4 (0.41) | — | |
| SCHEMBL4291393 | 0.86 | CYP1A2 (0.38) | — | |
| SCHEMBL19575870 | 0.86 | CYP1A2 (0.38) | — | |
| SCHEMBL28600615 | 0.85 | GRM4 (0.45) | — | |
| SCHEMBL180209 | 0.85 | GRM4 (0.45) | — | |
| Bromide SCHEMBL9657131 | 0.83 | GRM4 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 156 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114984324-B | Corrosion-resistant self-repairing coating for metal surface and preparation method thereof | 中国科学院大学宁波华美医院 | 2023-12-05 | — | — | CN | claimed |
| CN-114984324-A | Metal surface corrosion-resistant self-repairing coating and preparation method thereof | 中国科学院大学宁波华美医院 | 2022-09-02 | — | — | CN | claimed |
| CN-1056511-C | Process for preparing composition for beauty or pharmaceutical, especially dermtoses and anti-allergy and use | DIOR CHRISTIAN PARFUMS (FR) | 2000-09-20 | — | — | CN | claimed |
| US-5696273-A | Method for synthesizing cucurbitine | PARFUMS CHRISTIAN DIOR (FR) | 1997-12-09 | — | — | US | claimed |
| EP-0575454-B1 | USE OF CUCURBITINE FOR THE PREPARATION OF A COSMETIC OR PHARMACEUTICAL, PARTICULARLY DERMATOLOGICAL, ANTIALLERGIC COMPOSITION AND METHOD INVOLVING APPLICATION THEREOF | DIOR CHRISTIAN PARFUMS (FR) | 1997-08-27 | — | — | EP | claimed |
| US-5658885-A | OLIGOPEPTIDES; ANTICOAGULANTS; ENZYME INHIBITORS; THROMBIN | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-08-19 | — | — | US | claimed |
| CN-1065009-A | Use Cucurbitin preparation beauty treatment or medicinal, particularly dermatosis and antiallergic action with compositions and application process | DIOR CHRISTIAN PARFUMS (FR) | 1992-10-07 | — | — | CN | claimed |
| EP-4727654-A1 | DLL3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF | Mariana Oncology Inc. (US) | 2026-04-22 | — | — | EP | disclosed |
| EP-4727653-A1 | DLL3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF | Mariana Oncology Inc. (US) | 2026-04-22 | — | — | EP | disclosed |
| EP-4729094-A2 | Modulators of complement activity | UCB Holdings, Inc. (US) | 2026-04-22 | — | — | EP | disclosed |
| EP-4727655-A1 | DLL3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF | Mariana Oncology Inc. (US) | 2026-04-22 | — | — | EP | disclosed |
| US-12558398-B2 | Inflammatory disease treatment with complement inhibitors | UCB HOLDINGS, INC. (US) | 2026-02-24 | — | — | US | disclosed |
| EP-4218790-B1 | MODULATORS OF COMPLEMENT ACTIVITY | UCB HOLDINGS INC (US) | 2026-02-18 | — | — | EP | disclosed |
| US-5714164-A | Method for treatment of allergic disorders and cosmetic compositions using cucurbitine | PARFUMS CHRISTIAN DIOR (FR) | 1998-02-03 | — | — | US | disclosed |
| US-5696273-A | Method for synthesizing cucurbitine | PARFUMS CHRISTIAN DIOR (FR) | 1997-12-09 | — | — | US | disclosed |
| US-5658885-A | OLIGOPEPTIDES; ANTICOAGULANTS; ENZYME INHIBITORS; THROMBIN | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-08-19 | — | — | US | disclosed |
| EP-0787010-A1 | AMIDINO AND GUANIDINO SUBSTITUTED INHIBITORS OF TRYPSIN-LIKE ENZYMES | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-08-06 | — | — | EP | disclosed |
| US-5653997-A | ANTIHISTAMINE | PARFUMS CHRISTIAN DIOR (FR) | 1997-08-05 | — | — | US | disclosed |
| WO-1996012499-A1 | AMIDINO AND GUANIDINO SUBSTITUTED INHIBITORS OF TRYPSIN-LIKE ENZYMES | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-05-02 | — | — | WO | disclosed |
| CN-1065009-A | Use Cucurbitin preparation beauty treatment or medicinal, particularly dermatosis and antiallergic action with compositions and application process | DIOR CHRISTIAN PARFUMS (FR) | 1992-10-07 | — | — | CN | disclosed |