SCHEMBL180209

SCHEMBL180209

NC1(C(=O)O)CCNCC1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM4 Q14833 8/20 0.45
CYP1A2 P05177 4/20 0.45
GRM2 Q14416 3/20 0.45
GRM3 Q14832 3/20 0.45
CYP2C19 P33261 3/20 0.45
ALOX15 P16050 3/20 0.45
TDP1 Q9NUW8 2/20 0.45
GRM8 O00222 2/20 0.45
GRM6 O15303 2/20 0.45
LMNA P02545 1/20 0.45
GRM5 P41594 1/20 0.45
MTOR P42345 1/20 0.45
GRM1 Q13255 1/20 0.45
PLCB1 Q9NQ66 1/20 0.45
TSHR P16473 1/20 0.45
NSD2 O96028 1/20 0.44
DPP9 Q86TI2 1/20 0.43
DPP7 Q9UHL4 1/20 0.43
ALDH1A1 P00352 2/20 0.41
KMT2A Q03164 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28600615 1.00 GRM4 (0.45) GRM4CYP1A2GRM2GRM3CYP2C19
Bromide SCHEMBL9657131 0.97 GRM4 (0.43) GRM4CYP1A2GRM2GRM3CYP2C19
Hydrochloric Acid SCHEMBL2991552 0.97 GRM4 (0.43) GRM4CYP1A2GRM2GRM3CYP2C19
Trifluoroacetic Acid SCHEMBL29456819 0.87 GRM4 (0.37) GRM4CYP1A2GRM2GRM3CYP2C19
SCHEMBL29956680 0.85
SCHEMBL1433577 0.85
SCHEMBL28595938 0.85
Hydrochloric Acid SCHEMBL25279878 0.83 GRM4 (0.41) GRM4CYP1A2GRM2GRM3CYP2C19
Hydrochloric Acid SCHEMBL28913902 0.83 GRM4 (0.41) GRM4CYP1A2GRM2GRM3CYP2C19
Hydrochloric Acid SCHEMBL28913901 0.83 GRM4 (0.41) GRM4CYP1A2GRM2GRM3CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1732 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4719486-A1 CONJUGATES AND USES THEREOF Full-Life Technologies UK Limited (GB) 2026-04-08 EP claimed
EP-4719498-A1 RADIOLIGANDS FOR TARGETING CELL SURFACE RECEPTORS AND USES THEREOF Full-Life Technologies UK Limited (GB) 2026-04-08 EP claimed
US-12576169-B2 Silicon-fluoride acceptor substituted radiopharmaceuticals and precursors thereof Technische Universität München (DE) 2026-03-17 US claimed
EP-4696700-A1 LONG-ACTING K-OPIOID RECEPTOR AGONIST Chengdu Aoda Biotechnology Co., Ltd (CN) 2026-02-18 EP claimed
EP-4696699-A1 ? OPIOID RECEPTOR AGONIST AND USE THEREOF Chengdu Aoda Biotechnology Co., Ltd. (CN) 2026-02-18 EP claimed
US-12534498-B2 Compounds for use as apelin receptor antagonists CAMBRIDGE ENTERPRISE LIMITED (GB) 2026-01-27 US claimed
US-20260001928-A1 CRF2 RECEPTOR AGONISTS AND THEIR USE IN THERAPY CORTERIA PHARMACEUTICALS (FR) 2026-01-01 US claimed
EP-4482578-B1 CRF2 RECEPTOR AGONISTS AND THEIR USE IN THERAPY CORTERIA PHARMACEUTICALS (FR) 2025-12-24 EP claimed
US-12428447-B2 Peptide-based non-proteinaceous cargo delivery FELDAN BIO INC. (CA) 2025-09-30 US claimed
EP-4619043-A1 FIBROBLAST ACTIVATION PROTEIN TARGETED COMPOUNDS AND USE THEREOF Perspective Therapeutics, Inc. (US) 2025-09-24 EP claimed
EP-0958305-B1 INHIBITIONS OF THE INTERACTION BETWEEN P53 AND MDM2 CANCER REC TECH LTD (GB) 2008-06-04 EP claimed
EP-1917020-A1 MONOMETHYLVALINE COMPOUNDS HAVING PHENYLALANINE SIDE-CHAIN MODIFICATIONS AT THE C-TERMINUS Seattle Genetics, Inc. (US) 2008-05-07 EP claimed
WO-2008033119-A1 NOVEL COMBINATIONS OF DNAK INHIBITORS WITH KNOWN ANTIBACTERIAL AGENTS CHAPERONE TECHNOLOGIES, INC. (US) 2008-03-20 WO claimed
US-7262163-B2 Short amphipathic peptides with activity against bacteria and intracellular pathogens BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) 2007-08-28 US claimed
WO-2007008603-A1 MONOMETHYLVALINE COMPOUNDS HAVING PHENYLALANINE SIDE-CHAIN MODIFICATIONS AT THE C-TERMINUS SEATTLE GENETICS, INC. (US) 2007-01-18 WO claimed
US-20060287238-A1 Novel combinations of DnaK inhibitors with known antibacterial agents CHAPERONE TECHNOLOGIES, INC. 2006-12-21 US claimed
US-20050137137-A1 Inhibitors of the Interaction between p53 and MDM2 LANE DAVID P (GB) 2005-06-23 US claimed
US-20040059088-A1 Short amphipathic peptides with activity against bacteria and intracellular pathogens MCLAUGHLIN MARK L (US) 2004-03-25 US claimed
US-6566334-B1 For therapy of bacterial infection BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE 2003-05-20 US claimed
WO-1993000359-A1 MODIFIED PEPTIDES TRANSPORTABLE INTO THE CENTRAL NERVOUS SYSTEM THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1993-01-07 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12534498-B2 Compounds for use as apelin receptor antagonists APLNR, NPBWR1, AP3B1 GRM4 675/4885CYP1A2 4661/4885GRM2 816/4885
US-20060287238-A1 Novel combinations of DnaK inhibitors with known antibacterial agents DCK, DTYMK, POLK GRM4 4715/4885CYP1A2 4762/4885GRM2 4672/4885
US-20040059088-A1 Short amphipathic peptides with activity against bacteria and intracellular pathogens VIP, MDK, HM13 GRM4 4379/4885CYP1A2 4880/4885GRM2 4555/4885
US-12576169-B2 Silicon-fluoride acceptor substituted radiopharmaceuticals and precursors thereof KLK3, FOLH1, SLC7A1 GRM4 1780/4885CYP1A2 4726/4885GRM2 959/4885
US-20260001928-A1 CRF2 RECEPTOR AGONISTS AND THEIR USE IN THERAPY GIPR, NPY2R, NPY1R GRM4 63/4885CYP1A2 4024/4885GRM2 28/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.