Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | HTR2A | P28223 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | HRH1 | P35367 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | THPO | P40225 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13867520 | 0.85 | HTR2A (0.50) | CYP3A4TP53HTR2AKDM4ELMNA | |
| SCHEMBL14337103 | 0.83 | EGFR (0.46) | CYP3A4TP53HTR2AKDM4ELMNA | |
| SCHEMBL11724087 | 0.74 | KDM4E (0.69) | CYP3A4TP53HTR2AKDM4ELMNA | |
| SCHEMBL28746040 | 0.73 | CYP3A4 (0.42) | CYP3A4TP53HTR2AKDM4ELMNA | |
| SCHEMBL3874745 | 0.72 | HTR2A (0.61) | CYP3A4TP53HTR2AKDM4ELMNA | |
| SCHEMBL13303151 | 0.72 | DYRK1A (0.44) | CYP3A4TP53HTR2ALMNAALDH1A1 | |
| SCHEMBL313685 | 0.69 | ACHE (0.55) | CYP3A4TP53HTR2AKDM4ELMNA | |
| SCHEMBL10842525 | 0.69 | P2RX4 (0.41) | CYP3A4TP53HTR2AKDM4ELMNA | |
| SCHEMBL11721748 | 0.69 | HTR2A (0.57) | CYP3A4TP53HTR2AKDM4ELMNA | |
| SCHEMBL11725316 | 0.69 | HTR2A (0.71) | CYP3A4TP53HTR2AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7309718-B2 | Dibenzocycloheptene compound | UBE INDUSTRIES, LTD. (JP) | 2007-12-18 | — | — | US | disclosed |