SCHEMBL14337372

SCHEMBL14337372

O=C(O)c1cc2cccc(/C=N/c3ccccc3)c2[nH]1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.52
HPGD P15428 3/20 0.52
ALDH1A1 P00352 3/20 0.52
KMT2A Q03164 2/20 0.52
MEN1 O00255 1/20 0.52
USP2 O75604 1/20 0.52
APEX1 P27695 1/20 0.48
KDM4E B2RXH2 4/20 0.46
MAPT P10636 1/20 0.46
DAO P14920 1/20 0.46
SRD5A2 P31213 1/20 0.46
TSHR P16473 1/20 0.46
MGAM O43451 2/20 0.39
GAA P10253 2/20 0.39
SI P14410 2/20 0.39
MGAM2 Q2M2H8 2/20 0.39
NSD2 O96028 1/20 0.39
LMNA P02545 2/20 0.38
SIRT2 Q8IXJ6 1/20 0.38
EIF4A3 P38919 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14337435 0.83 MAPT (0.51) HSD17B10HPGDALDH1A1KMT2AMEN1
SCHEMBL6521130 0.79 HPGD (0.57) HSD17B10HPGDALDH1A1KMT2AMEN1
SCHEMBL14337187 0.78 ALDH1A1 (0.39) HPGDALDH1A1KMT2AMEN1KDM4E
SCHEMBL6513770 0.78 HPGD (0.55) HSD17B10HPGDALDH1A1KMT2AMEN1
SCHEMBL6521763 0.78 HPGD (0.55) HSD17B10HPGDALDH1A1KMT2AMEN1
SCHEMBL14337316 0.77 DHODH (0.47) ALDH1A1KMT2AMEN1KDM4EMAPT
SCHEMBL14337503 0.75 MAPT (0.39) HSD17B10HPGDALDH1A1KMT2AMEN1
SCHEMBL14337506 0.72 CDC7 (0.40) HPGDDHODH
SCHEMBL14337189 0.72 KDM5A (0.34) ALDH1A1KMT2AMEN1KDM4EMAPT
SCHEMBL17136028 0.72 HSD17B10 (0.64) HSD17B10HPGDALDH1A1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7312284-B2 Process for producing polar olefin copolymer and polar olefin copolymer obtained thereby MITSUI CHEMICALS, INC. (JP) 2007-12-25 US disclosed
US-7312284-B2 Process for producing polar olefin copolymer and polar olefin copolymer obtained thereby MITSUI CHEMICALS, INC. (JP) 2007-12-25 US disclosed