SCHEMBL14337489

SCHEMBL14337489

Oc1c(/C=N/c2ccccc2)ccc2ccccc12

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 10/20 0.64
MAPT P10636 9/20 0.61
ALDH1A1 P00352 6/20 0.57
CASP1 P29466 1/20 0.57
CASP7 P55210 1/20 0.57
MEN1 O00255 7/20 0.54
KDM4E B2RXH2 4/20 0.54
GAA P10253 4/20 0.54
L3MBTL1 Q9Y468 3/20 0.54
THRB P10828 2/20 0.54
POLB P06746 2/20 0.54
BLM P54132 1/20 0.54
CASP6 P55212 1/20 0.54
TDP2 O95551 1/20 0.53
HPGD P15428 1/20 0.53
RECQL P46063 1/20 0.53
HKDC1 Q2TB90 1/20 0.51
SIRT2 Q8IXJ6 1/20 0.50
TDP1 Q9NUW8 3/20 0.49
LMNA P02545 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14337245 0.81 POLB (0.52) KMT2AMAPTALDH1A1MEN1KDM4E
SCHEMBL11770105 0.80 MAPT (0.54) KMT2AMAPTALDH1A1CASP1CASP7
SCHEMBL8942519 0.80 MAPT (0.54) KMT2AMAPTALDH1A1CASP1CASP7
SCHEMBL8942514 0.80 MAPT (0.54) KMT2AMAPTALDH1A1CASP1CASP7
SCHEMBL30704461 0.80 KMT2A (0.58) KMT2AMAPTALDH1A1CASP1CASP7
SCHEMBL22914874 0.80 KMT2A (0.58) KMT2AMAPTALDH1A1CASP1CASP7
SCHEMBL2316368 0.79 KMT2A (0.52) KMT2AMAPTALDH1A1CASP1CASP7
SCHEMBL9305089 0.78 MAPT (0.54) KMT2AMAPTALDH1A1MEN1KDM4E
SCHEMBL9305094 0.78 MAPT (0.54) KMT2AMAPTALDH1A1MEN1KDM4E
SCHEMBL14365932 0.78 KMT2A (0.55) KMT2AMAPTALDH1A1CASP1CASP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1170308-B1 Process for producing a copolymer of a non-polar olefin and a polar olefin MITSUI CHEMICALS INC (JP) 2015-05-06 EP disclosed
US-7312284-B2 Process for producing polar olefin copolymer and polar olefin copolymer obtained thereby MITSUI CHEMICALS, INC. (JP) 2007-12-25 US disclosed
US-7312284-B2 Process for producing polar olefin copolymer and polar olefin copolymer obtained thereby MITSUI CHEMICALS, INC. (JP) 2007-12-25 US disclosed
US-7300903-B2 Olefin polymerization catalysts, transition metal compounds, processes for olefin polymerization, and α-olefin/conjugated diene copolymers MITSUI CHEMICALS, INC. (JP) 2007-11-27 US disclosed
US-7300903-B2 Olefin polymerization catalysts, transition metal compounds, processes for olefin polymerization, and α-olefin/conjugated diene copolymers MITSUI CHEMICALS, INC. (JP) 2007-11-27 US disclosed
EP-1832609-A2 Process for producing a copolymer of a non-polar olefin and a polar olefin and the copolymer obtained thereby Mitsui Chemicals, Inc. (JP) 2007-09-12 EP disclosed