Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.36 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.36 |
| ▸ | TERT | O14746 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12314665 | 1.00 | CYP3A4 (0.47) | CYP3A4CYP19A1FFAR1PPARGPPARD | |
| SCHEMBL14076892 | 0.90 | MEN1 (0.48) | CYP3A4MAOBMEN1MAPTTHRB | |
| SCHEMBL12749671 | 0.90 | MEN1 (0.48) | CYP3A4MAOBMEN1MAPTTHRB | |
| SCHEMBL12992985 | 0.85 | LMNA (0.44) | CYP3A4CYP19A1FFAR1PPARGPPARD | |
| SCHEMBL12993092 | 0.85 | LMNA (0.44) | CYP3A4CYP19A1FFAR1PPARGPPARD | |
| SCHEMBL17985005 | 0.84 | CYP3A4 (0.60) | CYP3A4CYP19A1MAOBLTB4RLTB4R2 | |
| SCHEMBL2742797 | 0.84 | CYP3A4 (0.43) | CYP3A4CYP19A1FFAR1PPARGPPARD | |
| SCHEMBL149887 | 0.79 | CYP3A4 (0.49) | CYP3A4MAOB | |
| SCHEMBL12255070 | 0.79 | CYP3A4 (0.49) | CYP3A4MAOB | |
| SCHEMBL2070165 | 0.79 | CYP3A4 (0.49) | CYP3A4MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8263790-B2 | Method for enantioselective hydrogenation of chromenes | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2012-09-11 | — | — | US | disclosed |
| US-7312344-B2 | Dimeric isoflavones | NOVOGEN RESEARCH PTY LIMITED (AU) | 2007-12-25 | — | — | US | disclosed |