Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 7/20 | 0.91 |
| ▸ | PGR | P06401 | 5/20 | 0.91 |
| ▸ | MAPT | P10636 | 3/20 | 0.91 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.91 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.91 |
| ▸ | DRD2 | P14416 | 1/20 | 0.91 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.91 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.77 |
| ▸ | USP2 | O75604 | 5/20 | 0.77 |
| ▸ | MEN1 | O00255 | 1/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.77 |
| ▸ | LMNA | P02545 | 3/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.77 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.77 |
| ▸ | MLNR | O43193 | 1/20 | 0.77 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.77 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.77 |
| ▸ | PPARG | P37231 | 1/20 | 0.77 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.77 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Betamethasone Butyrate Propionate SCHEMBL120208 | 1.00 | NR3C1 (0.91) | NR3C1PGRMAPTNR1I2ADORA3 | |
| SCHEMBL9768458 | 0.97 | NR3C1 (0.91) | NR3C1PGRMAPTNR1I2ADORA3 | |
| SCHEMBL10864822 | 0.97 | NR3C1 (0.91) | NR3C1PGRMAPTNR1I2ADORA3 | |
| SCHEMBL10865493 | 0.97 | NR3C1 (0.91) | NR3C1PGRMAPTNR1I2ADORA3 | |
| SCHEMBL9768460 | 0.97 | NR3C1 (0.91) | NR3C1PGRMAPTNR1I2ADORA3 | |
| SCHEMBL9157442 | 0.97 | NR3C1 (0.85) | NR3C1PGRMAPTNR1I2ADORA3 | |
| SCHEMBL11520052 | 0.96 | NR3C1 (0.90) | NR3C1PGRMAPTNR1I2ADORA3 | |
| Betamethasone Dipropionate SCHEMBL9768468 | 0.95 | NR3C1 (1.00) | NR3C1PGRMAPTNR1I2ADORA3 | |
| Betamethasone Dipropionate SCHEMBL10013893 | 0.95 | NR3C1 (1.00) | NR3C1PGRMAPTNR1I2ADORA3 | |
| Betamethasone Dipropionate SCHEMBL20097870 | 0.95 | NR3C1 (1.00) | NR3C1PGRMAPTNR1I2ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070287689-A1 | Therapeutic And/Or Preventive Agents For Chronic Skin Diseases | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070287689-A1 | Therapeutic And/Or Preventive Agents For Chronic Skin Diseases | PDE4A, PDE3B, PDE2A | NR3C1 62/4885PGR 1575/4885MAPT 4688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.