Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 20/20 | 1.00 |
| ▸ | KCNQ2 | O43526 | 20/20 | 1.00 |
| ▸ | KCNE1 | P15382 | 13/20 | 1.00 |
| ▸ | KCNQ1 | P51787 | 13/20 | 1.00 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.75 |
| ▸ | BACE1 | P56817 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL367538 | 0.90 | KCNQ3 (1.00) | KCNQ3KCNQ2KCNE1KCNQ1KCNQ5 | |
| SCHEMBL5215833 | 0.89 | KCNQ3 (1.00) | KCNQ3KCNQ2KCNE1KCNQ1BACE1 | |
| SCHEMBL5214441 | 0.87 | KCNQ3 (1.00) | KCNQ3KCNQ2KCNE1KCNQ1BACE1 | |
| SCHEMBL5214671 | 0.86 | KCNQ3 (0.78) | KCNQ3KCNQ2KCNE1KCNQ1BACE1 | |
| SCHEMBL5348385 | 0.86 | KCNQ3 (1.00) | KCNQ3KCNQ2KCNE1KCNQ1KCNQ5 | |
| SCHEMBL6086341 | 0.85 | KCNQ3 (0.76) | KCNQ3KCNQ2KCNE1KCNQ1BACE1 | |
| SCHEMBL5216578 | 0.84 | KCNQ3 (1.00) | KCNQ3KCNQ2KCNE1KCNQ1BACE1 | |
| SCHEMBL5214418 | 0.84 | KCNQ3 (1.00) | KCNQ3KCNQ2KCNE1KCNQ1BACE1 | |
| SCHEMBL5217182 | 0.83 | KCNQ3 (0.73) | KCNQ3KCNQ2KCNE1KCNQ1BACE1 | |
| SCHEMBL5217786 | 0.82 | KCNQ3 (0.71) | KCNQ3KCNQ2KCNE1KCNQ1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1208085-B1 | BENZANILIDES AS POTASSIUM CHANNEL OPENERS | ICAGEN INC (US) | 2007-12-05 | — | — | EP | disclosed |