Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 0.51 |
| ▸ | NR3C2 | P08235 | 15/20 | 0.51 |
| ▸ | PGR | P06401 | 12/20 | 0.51 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1634059 | 0.90 | NR3C1 (0.61) | NR3C1NR3C2PGR | |
| SCHEMBL1633498 | 0.85 | NR3C1 (0.55) | NR3C1NR3C2PGR | |
| SCHEMBL1634313 | 0.80 | NR3C1 (0.60) | NR3C1NR3C2PGR | |
| SCHEMBL1633783 | 0.80 | NR3C1 (0.60) | NR3C1NR3C2PGR | |
| SCHEMBL292336 | 0.78 | NR3C1 (0.63) | NR3C1NR3C2PGR | |
| SCHEMBL1634425 | 0.77 | NR3C1 (0.46) | NR3C1NR3C2PGR | |
| SCHEMBL1633470 | 0.77 | NR3C1 (0.58) | NR3C1NR3C2PGRAR | |
| SCHEMBL6638176 | 0.74 | NR3C1 (0.49) | NR3C1NR3C2PGRAR | |
| SCHEMBL1633963 | 0.72 | NR3C1 (0.53) | NR3C1NR3C2PGRAR | |
| SCHEMBL1634084 | 0.71 | NR3C1 (0.52) | NR3C1NR3C2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1490062-B1 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM PHARMA (US) | 2007-12-19 | — | — | EP | disclosed |