Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 7/20 | 0.61 |
| ▸ | HTT | P42858 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | NAAA | Q02083 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | SORD | Q00796 | 2/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | PHGDH | O43175 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12162756 | 0.87 | KMT2A (0.72) | KMT2AGAALMNAHTTSMN1; SMN2 | |
| SCHEMBL14942669 | 0.82 | KMT2A (0.66) | KMT2AGAALMNAHTTSMN1; SMN2 | |
| SCHEMBL389868 | 0.81 | GAA (0.64) | KMT2AGAALMNAHTTSMN1; SMN2 | |
| SCHEMBL4058660 | 0.79 | GAA (0.64) | KMT2AGAALMNAHTTSMN1; SMN2 | |
| SCHEMBL5318590 | 0.79 | GAA (0.67) | KMT2AGAALMNAHTTSMN1; SMN2 | |
| SCHEMBL880471 | 0.76 | GAA (0.64) | KMT2AGAALMNAHTTSMN1; SMN2 | |
| SCHEMBL22489503 | 0.76 | KMT2A (0.60) | KMT2AGAALMNAHTTSMN1; SMN2 | |
| SCHEMBL3264562 | 0.75 | GAA (0.59) | KMT2AGAALMNAHTTSMN1; SMN2 | |
| SCHEMBL19630535 | 0.73 | NAAA (1.00) | KMT2AGAALMNAHTTSMN1; SMN2 | |
| SCHEMBL14071936 | 0.73 | GAA (0.63) | KMT2AGAALMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1870401-A1 | 1,4-SUBSTITUTED PIPERAZINE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-12-26 | — | — | EP | disclosed |