Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL391005 | 0.82 | PARP1 (0.54) | ALDH1A1KMT2AKDM4EHSD17B10CYP3A4 | |
| SCHEMBL388707 | 0.81 | MAPT (0.49) | ALDH1A1MAPTKMT2AHPGDSMN1; SMN2 | |
| SCHEMBL14340758 | 0.80 | HSD17B10 (0.52) | ALDH1A1MAPTKMT2APOLBKDM4E | |
| SCHEMBL29265204 | 0.80 | ALDH1A1 (0.63) | ALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL14340875 | 0.80 | MAPT (0.55) | ALDH1A1MAPTKMT2AKDM4EHSD17B10 | |
| SCHEMBL388870 | 0.79 | PANK3 (0.53) | ALDH1A1KMT2AKDM4EHSD17B10CYP3A4 | |
| SCHEMBL10168032 | 0.79 | HSD17B10 (0.44) | ALDH1A1KMT2AKDM4EHSD17B10CYP3A4 | |
| SCHEMBL14340860 | 0.77 | KDM4E (0.70) | ALDH1A1KMT2APOLBKDM4EHSD17B10 | |
| SCHEMBL391613 | 0.76 | KDM4E (0.41) | ALDH1A1KMT2AKDM4EHSD17B10CYP3A4 | |
| SCHEMBL391614 | 0.76 | KDM4E (0.41) | ALDH1A1KMT2AKDM4EHSD17B10CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1870401-A1 | 1,4-SUBSTITUTED PIPERAZINE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-12-26 | — | — | EP | disclosed |