⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28486390 | 0.81 | — | — | |
| SCHEMBL76625 | 0.72 | — | — | |
| Phosphine SCHEMBL21227051 | 0.69 | CA2 (0.42) | — | |
| SCHEMBL13284809 | 0.69 | CA2 (0.42) | — | |
| SCHEMBL1014584 | 0.69 | — | — | |
| SCHEMBL17052578 | 0.69 | CA2 (0.42) | — | |
| SCHEMBL8731771 | 0.69 | CA2 (0.42) | — | |
| SCHEMBL20853030 | 0.67 | — | — | |
| SCHEMBL6594058 | 0.67 | — | — | |
| SCHEMBL12230314 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170072016-A1 | TREATMENT OF NEONATAL BRAIN INJURY WITH HB-EGF | CHILDREN'S NATIONAL MEDICAL CENTER (US) | 2017-03-16 | — | — | US | disclosed |
| EP-1226935-B1 | Method and apparatus for manufacturing laminated material | TOYO SEIKAN KAISHA LTD (JP) | 2007-12-12 | — | — | EP | disclosed |