SCHEMBL14341807

SCHEMBL14341807

CC12CCCC1C(=O)OC2=O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.36
TP53 P04637 3/20 0.36
MAPK1 P28482 3/20 0.36
HIF1A Q16665 2/20 0.36
LMNA P02545 2/20 0.36
CYP1A2 P05177 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
TSHR P16473 2/20 0.36
NFKB1 P19838 1/20 0.36
THPO P40225 1/20 0.36
PPM1B O75688 1/20 0.36
PTPN1 P18031 1/20 0.36
PPP1CC P36873 1/20 0.36
TFPI2 P48307 1/20 0.36
PPP5C P53041 1/20 0.36
PPP2CA P67775 1/20 0.36
PPP1CA P62136 1/20 0.36
KDM4E B2RXH2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29292154 1.00 CYP3A4 (0.36) CYP3A4TP53MAPK1HIF1ALMNA
SCHEMBL15660 0.94 TP53 (0.35) CYP3A4TP53MAPK1HIF1ALMNA
SCHEMBL9617808 0.94 TP53 (0.35) CYP3A4TP53MAPK1HIF1ALMNA
SCHEMBL9617806 0.94 TP53 (0.35) CYP3A4TP53MAPK1HIF1ALMNA
Hydrochloric Acid SCHEMBL29273337 0.90 HTT (0.34) CYP3A4TP53MAPK1HIF1ALMNA
SCHEMBL11257689 0.89 LMNA (0.40) CYP3A4TP53MAPK1HIF1ALMNA
Propane SCHEMBL8670036 0.89 TP53 (0.32) CYP3A4TP53MAPK1HIF1ALMNA
SCHEMBL4936681 0.86 HTT (0.32) CYP3A4TP53MAPK1HIF1ALMNA
1,6-Hexanediol SCHEMBL9364138 0.82 CYP4F2 (0.33) LMNATSHR
SCHEMBL8670369 0.81 LMNA (0.30) LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1168066-B1 Silver salt photothermographic dry imaging material KONICA CORP (JP) 2007-12-05 EP disclosed
EP-1099977-B1 Preparation method of photothermographic material KONICA CORP (JP) 2007-04-11 EP disclosed