Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 10/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14343570 | 0.89 | EPHX1 (0.61) | EPHX1EPHX2ALDH1A1SMN1; SMN2 | |
| SCHEMBL14343846 | 0.84 | NPC1 (0.51) | EPHX1EPHX2ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL28612121 | 0.74 | EPHX1 (1.00) | EPHX1EPHX2 | |
| SCHEMBL15741883 | 0.74 | EPHX1 (1.00) | EPHX1EPHX2 | |
| SCHEMBL1066578 | 0.74 | EPHX1 (1.00) | EPHX1EPHX2 | |
| SCHEMBL1065387 | 0.74 | EPHX1 (1.00) | EPHX1EPHX2 | |
| SCHEMBL14343558 | 0.71 | SMN1; SMN2 (0.50) | EPHX1EPHX2ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL14343076 | 0.71 | SMN1; SMN2 (0.50) | EPHX1EPHX2ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL14343422 | 0.69 | EPHX2 (0.44) | EPHX2ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL15480466 | 0.69 | SMN1; SMN2 (0.81) | EPHX1EPHX2ALDH1A1SMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007150011-A2 | PROLYL HYDROXYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-12-27 | — | — | WO | disclosed |