Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | PKM | P14618 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ILK | Q13418 | 2/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.37 |
| ▸ | VDR | P11473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4194631 | 0.90 | ALDH1A1 (0.46) | ALDH1A1LMNAPKMMAPTHSD17B10 | |
| SCHEMBL4197657 | 0.86 | ALDH1A1 (0.44) | ALDH1A1LMNAPKMMAPTHSD17B10 | |
| SCHEMBL4186018 | 0.86 | ALDH1A1 (0.43) | ALDH1A1LMNAPKMMAPTHSD17B10 | |
| SCHEMBL4200050 | 0.83 | ALDH1A1 (0.41) | ALDH1A1LMNAPKMMAPTHSD17B10 | |
| SCHEMBL4192953 | 0.79 | MAPT (0.47) | ALDH1A1LMNAPKMMAPTHSD17B10 | |
| SCHEMBL4194915 | 0.76 | ALDH1A1 (0.44) | ALDH1A1LMNAPKMMAPTHTT | |
| SCHEMBL4190737 | 0.76 | ALDH1A1 (0.43) | ALDH1A1LMNAPKMMAPTHTT | |
| SCHEMBL4193911 | 0.74 | ALDH1A1 (0.43) | ALDH1A1LMNAPKMMAPTHTT | |
| SCHEMBL4192343 | 0.73 | ALDH1A1 (0.47) | ALDH1A1LMNAPKMHSD17B10HTT | |
| SCHEMBL4192945 | 0.73 | ALDH1A1 (0.48) | ALDH1A1LMNAPKMMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879877-B1 | ANTIMICROBIAL AGENTS | RANBAXY LAB LTD (IN) | 2013-01-02 | — | — | EP | claimed |