Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 13/20 | 0.40 |
| ▸ | MEN1 | O00255 | 12/20 | 0.40 |
| ▸ | USP2 | O75604 | 8/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 5/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 4/20 | 0.39 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | HTT | P42858 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | RGS12 | O14924 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14344531 | 0.95 | KMT2A (0.43) | KMT2AMEN1USP2ALDH1A1KEAP1 | |
| SCHEMBL14092686 | 0.86 | KMT2A (0.54) | KMT2AMEN1USP2ALDH1A1KEAP1 | |
| SCHEMBL14278202 | 0.75 | CDK2 (0.39) | KMT2AMEN1USP2ALDH1A1KDM4E | |
| SCHEMBL9006289 | 0.70 | KMT2A (0.65) | KMT2AMEN1USP2ALDH1A1KEAP1 | |
| SCHEMBL24030622 | 0.70 | HSD17B10 (0.50) | ALDH1A1KEAP1NFE2L2KDM4EATM | |
| SCHEMBL13227945 | 0.69 | MEN1 (0.41) | KMT2AMEN1USP2ALDH1A1KEAP1 | |
| SCHEMBL14195097 | 0.69 | CDK2 (0.40) | KMT2AMEN1USP2ALDH1A1KDM4E | |
| SCHEMBL10832427 | 0.69 | KMT2A (0.50) | KMT2AMEN1USP2ALDH1A1KEAP1 | |
| SCHEMBL16786419 | 0.66 | MEN1 (0.32) | KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL9290413 | 0.65 | PKM (0.57) | KMT2AMEN1USP2ALDH1A1KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7309552-B2 | Containing the reaction product of a dibenzo [a,c]phenadine-2,7-bisdiazonium salt and a coupler such as N-benzyl-2-hydroxy-7,8-naphthalic acid imide; stilbene charge transport material; 1alkylidene-2,3-diphenylindene acceptor; biphenol; copolycarbonate containing arylamine groups; highly durable | RICOH COMPANY, LTD. (JP) | 2007-12-18 | — | — | US | disclosed |