Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | PPARA | Q07869 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | PPARD | Q03181 | 3/20 | 0.51 |
| ▸ | PPARG | P37231 | 2/20 | 0.51 |
| ▸ | FABP2 | P12104 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5328307 | 0.82 | POLB (0.52) | TP53PPARAALDH1A1PPARDPPARG | |
| SCHEMBL14345085 | 0.82 | PPARA (0.49) | PPARAPPARDPPARGNPC1RAB9A | |
| SCHEMBL14345472 | 0.81 | PPARA (0.52) | PPARAALDH1A1PPARDPPARGFABP2 | |
| SCHEMBL14345585 | 0.80 | PPARA (0.60) | PPARAPPARDPPARG | |
| SCHEMBL14345202 | 0.78 | USP2 (0.56) | PPARAALDH1A1PPARGSMN1; SMN2MAPT | |
| SCHEMBL14345084 | 0.78 | PPARA (0.52) | PPARAPPARDPPARG | |
| SCHEMBL5327164 | 0.78 | PPARA (0.54) | PPARAALDH1A1PPARDPPARGFABP2 | |
| SCHEMBL14345563 | 0.77 | PPARA (0.52) | PPARAALDH1A1PPARDPPARGFABP2 | |
| SCHEMBL14345509 | 0.76 | PPARA (0.59) | TP53PPARAPPARDPPARGSMN1; SMN2 | |
| SCHEMBL14345525 | 0.76 | PPARA (0.56) | TP53PPARAPPARDPPARGSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007141423-A1 | PPAR ENHANCING DERIVATIVES, METHOD FOR PREPARING SAME AND THERAPEUTIC USE THEREOF | NEGMA-LERADS (FR) | 2007-12-13 | — | — | WO | disclosed |