Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.48 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.48 |
| ▸ | PPARA | Q07869 | 5/20 | 0.47 |
| ▸ | PPARG | P37231 | 3/20 | 0.47 |
| ▸ | PPARD | Q03181 | 3/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | MET | P08581 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14345534 | 0.85 | MEN1 (0.58) | MEN1KMT2AALDH1A1PPARASMN1; SMN2 | |
| SCHEMBL14345525 | 0.83 | PPARA (0.56) | POLBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL14345085 | 0.82 | PPARA (0.49) | NPC1RAB9AAURKARPS6KB1AURKB | |
| SCHEMBL14345274 | 0.82 | TP53 (0.53) | POLBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL14345590 | 0.82 | PPARA (0.53) | POLBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL14345475 | 0.82 | PPARA (0.52) | MEN1KMT2ANPC1RAB9APPARA | |
| SCHEMBL5328303 | 0.82 | NPC1 (0.51) | POLBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL14345585 | 0.80 | PPARA (0.60) | PPARAPPARGPPARD | |
| SCHEMBL14345084 | 0.78 | PPARA (0.52) | PPARAPPARGPPARD | |
| SCHEMBL14345202 | 0.78 | USP2 (0.56) | KMT2ARAB9AALDH1A1PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007141423-A1 | PPAR ENHANCING DERIVATIVES, METHOD FOR PREPARING SAME AND THERAPEUTIC USE THEREOF | NEGMA-LERADS (FR) | 2007-12-13 | — | — | WO | disclosed |
| WO-2007141423-A1 | PPAR ENHANCING DERIVATIVES, METHOD FOR PREPARING SAME AND THERAPEUTIC USE THEREOF | NEGMA-LERADS (FR) | 2007-12-13 | — | — | WO | disclosed |