Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 13/20 | 0.55 |
| ▸ | ACACA | Q13085 | 13/20 | 0.55 |
| ▸ | GSK3B | P49841 | 3/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | PRKACA | P17612 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.35 |
| ▸ | MST1R | Q04912 | 1/20 | 0.35 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.35 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.35 |
| ▸ | CAMK1D | Q8IU85 | 1/20 | 0.35 |
| ▸ | TDP2 | O95551 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4546196 | 0.90 | ACACB (0.67) | ACACBACACAGSK3BJAK2NTRK1 | |
| SCHEMBL4546183 | 0.87 | ACACB (0.47) | ACACBACACAGSK3BJAK2NTRK1 | |
| SCHEMBL4550020 | 0.84 | ACACB (0.44) | ACACBACACAGSK3BJAK2NTRK1 | |
| SCHEMBL12136946 | 0.83 | ACACB (0.44) | ACACBACACAGSK3BGSK3ARECQL | |
| SCHEMBL4546185 | 0.82 | ACACB (0.50) | ACACBACACAGSK3BGSK3ARECQL | |
| SCHEMBL6113587 | 0.79 | ACACB (0.61) | ACACBACACAGSK3BJAK2NTRK1 | |
| SCHEMBL4546200 | 0.78 | ACACB (0.46) | ACACBACACARECQL | |
| SCHEMBL4546190 | 0.77 | ACACB (0.48) | ACACBACACARECQL | |
| SCHEMBL2347074 | 0.76 | ACACB (0.84) | ACACBACACAGSK3BJAK2NTRK1 | |
| SCHEMBL2351493 | 0.76 | ACACB (0.66) | ACACBACACAGSK3BJAK2NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007140881-A1 | ALKOXYALKYL-SUBSTITUTED CYCLIC KETO-ENOLS | BAYER CROPSCIENCE AG (DE) | 2007-12-13 | — | — | WO | disclosed |