SCHEMBL4546200

SCHEMBL4546200

CCc1cc(-c2ccc(Cl)cc2)cc(C)c1C1=C(O)C(C)(COC)NC1=O

nearest known ligand 0.46

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ACACB O00763 11/20 0.46
ACACA Q13085 11/20 0.46
RECQL P46063 1/20 0.30
CNR1 P21554 1/20 0.30
CNR2 P34972 1/20 0.30
ERN1 O75460 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4546185 0.93 ACACB (0.50) ACACBACACARECQLERN1
SCHEMBL4546201 0.85 ACACB (0.39) ACACBACACA
SCHEMBL4546199 0.84 ACACB (0.39) ACACBACACA
SCHEMBL812168 0.81 ACACB (0.40) ACACBACACARECQL
SCHEMBL4546196 0.81 ACACB (0.67) ACACBACACARECQL
SCHEMBL4546186 0.81 ACACB (0.42) ACACBACACARECQL
SCHEMBL12137010 0.81 ACACB (0.32) ACACBACACA
SCHEMBL4549943 0.80 ACACB (0.43) ACACBACACARECQLERN1
SCHEMBL4546190 0.79 ACACB (0.48) ACACBACACARECQL
SCHEMBL12136963 0.79 ACACB (0.39) ACACBACACA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8173697-B2 Alkoxyalkyl-substituted cyclic keto-enols BAYER CROPSCIENCE AG (DE) 2012-05-08 US disclosed
US-8173697-B2 Alkoxyalkyl-substituted cyclic keto-enols BAYER CROPSCIENCE AG (DE) 2012-05-08 US disclosed
US-20090298828-A1 Alkoxyalkyl-Substituted Cyclic Keto-Enols BAYER CROPSCIENCE AG (DE) 2009-12-03 US disclosed
US-20090298828-A1 Alkoxyalkyl-Substituted Cyclic Keto-Enols BAYER CROPSCIENCE AG (DE) 2009-12-03 US disclosed
WO-2007140881-A1 ALKOXYALKYL-SUBSTITUTED CYCLIC KETO-ENOLS BAYER CROPSCIENCE AG (DE) 2007-12-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090298828-A1 Alkoxyalkyl-Substituted Cyclic Keto-Enols DDT, AKR1D1, EBP ACACB 249/4885ACACA 529/4885RECQL 2752/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.