Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1768045 | 0.90 | TSHR (0.50) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL594507 | 0.86 | TSHR (0.57) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL12677361 | 0.86 | TSHR (0.57) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL1537333 | 0.82 | TSHR (0.57) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL311323 | 0.82 | TSHR (0.57) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL1004395 | 0.81 | TSHR (0.55) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL3195517 | 0.80 | TSHR (0.34) | TSHRMAPK1ALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL21023737 | 0.80 | TSHR (0.41) | TSHRMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL22394611 | 0.79 | TSHR (0.53) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL18085532 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007149501-A2 | PROCESS FOR PREPARING DENDRITIC POLYMERS USING MICROWAVE ASSISTED SYNTHESIS | DENDRITIC NANO TECHNOLOGIES, INC. (US) | 2007-12-27 | — | — | WO | disclosed |