SCHEMBL1768045

SCHEMBL1768045

C#CCOCC(COCC1CO1)(COCC1CO1)COCC1CO1

nearest known ligand 0.50

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.50
MAPK1 P28482 1/20 0.50
ALDH1A1 P00352 4/20 0.37
SMN1; SMN2 Q16637 1/20 0.36
TDP1 Q9NUW8 1/20 0.34
TP53 P04637 1/20 0.30
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14345780 0.90 TSHR (0.44) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
SCHEMBL21023737 0.85 TSHR (0.41) TSHRMAPK1ALDH1A1SMN1; SMN2
SCHEMBL260698 0.84
SCHEMBL18085532 0.84
SCHEMBL18085540 0.84
SCHEMBL36499 0.84 TSHR (0.67) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
SCHEMBL31646679 0.79 TSHR (0.56) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
SCHEMBL12629261 0.77 TSHR (0.54) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
SCHEMBL3183822 0.77 TSHR (0.34) TSHRMAPK1ALDH1A1
SCHEMBL15803995 0.75 TSHR (0.33) TSHRMAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7985424-B2 Dendritic polymers with enhanced amplification and interior functionality DENDRITIC NANOTECHNOLOGIES INC. (US) 2011-07-26 US claimed
EP-2325236-A1 Dendritic polymers with enhanced amplification and interior functionality Dendritic Nanotechnologies Inc. (US) 2011-05-25 EP claimed
JP-2008545621-A 2008-12-18 JP claimed
EP-1877103-A2 DENDRITIC POLYMERS WITH ENHANCED AMPLIFICATION AND INTERIOR FUNCTIONALITY Dendritic Nanotechnologies, Inc. (US) 2008-01-16 EP claimed
US-20070298006-A1 Dendritic Polymers With Enhanced Amplification and Interior Functionality DENDRITIC NANOTECHNOLOGIES, INC. (US) 2007-12-27 US claimed
WO-2006115547-A2 DENDRITIC POLYMERS WITH ENHANCED AMPLIFICATION AND INTERIOR FUNCTIONALITY DENDRITIC NANOTECHNOLOGIES, INC. (US) 2006-11-02 WO claimed
EP-2493291-B1 PEHAM DENDRIMERS FOR USE IN AGRICULTURE DENDRITIC NANOTECHNOLOGIES INC (US) 2019-05-22 EP disclosed
US-9585387-B1 PEHAM dendrimers for use in agriculture STARPHARMA PTY LTD (AU) 2017-03-07 US disclosed
US-9585387-B1 PEHAM dendrimers for use in agriculture STARPHARMA PTY LTD (AU) 2017-03-07 US disclosed
US-9585387-B1 PEHAM dendrimers for use in agriculture STARPHARMA PTY LTD (AU) 2017-03-07 US disclosed
EP-2493291-A1 PEHAM DENDRIMERS FOR USE IN AGRICULTURE Dendritic Nanotechnologies, Inc. (US) 2012-09-05 EP disclosed
US-20110230348-A1 PEHAM Dendrimers for Use in Agriculture DENDRITIC NANOTECHNOLOGIES, INC. (US) 2011-09-22 US disclosed
US-20110230348-A1 PEHAM Dendrimers for Use in Agriculture DENDRITIC NANOTECHNOLOGIES, INC. (US) 2011-09-22 US disclosed
WO-2008082627-A1 DIVERGENT SYNTHESIS OF LOOPED POLY (ESTER)-AND POLY (ETHER)- SUBSTITUTED DENDRONS AND DENDRIMERS DENDRITIC NANOTECHNOLOGIES, INC. (US) 2008-07-10 WO disclosed
EP-1877103-A2 DENDRITIC POLYMERS WITH ENHANCED AMPLIFICATION AND INTERIOR FUNCTIONALITY Dendritic Nanotechnologies, Inc. (US) 2008-01-16 EP disclosed
WO-2007149501-A2 PROCESS FOR PREPARING DENDRITIC POLYMERS USING MICROWAVE ASSISTED SYNTHESIS DENDRITIC NANO TECHNOLOGIES, INC. (US) 2007-12-27 WO disclosed
US-20070298006-A1 Dendritic Polymers With Enhanced Amplification and Interior Functionality DENDRITIC NANOTECHNOLOGIES, INC. (US) 2007-12-27 US disclosed
US-20070298006-A1 Dendritic Polymers With Enhanced Amplification and Interior Functionality DENDRITIC NANOTECHNOLOGIES, INC. (US) 2007-12-27 US disclosed
US-20070298006-A1 Dendritic Polymers With Enhanced Amplification and Interior Functionality DENDRITIC NANOTECHNOLOGIES, INC. (US) 2007-12-27 US disclosed
WO-2006115547-A2 DENDRITIC POLYMERS WITH ENHANCED AMPLIFICATION AND INTERIOR FUNCTIONALITY DENDRITIC NANOTECHNOLOGIES, INC. (US) 2006-11-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070298006-A1 Dendritic Polymers With Enhanced Amplification and Interior Functionality MYD88, TLR3, TMEM97 TSHR 3651/4885MAPK1 4174/4885ALDH1A1 2720/4885
US-20110230348-A1 PEHAM Dendrimers for Use in Agriculture MGAM, PGLS, CAT TSHR 3604/4885MAPK1 3249/4885ALDH1A1 2222/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.