⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11640496 | 1.00 | — | — | |
| SCHEMBL22321696 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL11366809 | 0.97 | LMNA (0.40) | — | |
| SCHEMBL21727837 | 0.87 | TRPV1 (0.38) | — | |
| SCHEMBL9184898 | 0.87 | TRPV1 (0.38) | — | |
| Hydrochloric Acid SCHEMBL9184947 | 0.83 | TRPV1 (0.36) | — | |
| SCHEMBL18538927 | 0.82 | LMNA (0.61) | — | |
| SCHEMBL22321680 | 0.82 | LMNA (0.53) | — | |
| SCHEMBL10556255 | 0.82 | LMNA (0.53) | — | |
| SCHEMBL19159678 | 0.82 | TRPV1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007150046-A2 | METHODS AND COMPOSITIONS FOR TREATING OPHTHALMIC CONDITIONS VIA MODULATION OF MEGALIN ACTIVITY | SIRION THERAPEUTICS, INC (US) | 2007-12-27 | — | — | WO | disclosed |