SCHEMBL14347307

SCHEMBL14347307

CC(C)(C)CC(NC(C)(C)C)C(=O)C(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GRN P28799 1/20 0.33
SORT1 Q99523 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12632051 1.00 GRN (0.33) GRNSORT1
SCHEMBL22548877 0.85
SCHEMBL14347369 0.83
SCHEMBL14347362 0.82 PIK3CD (0.32)
SCHEMBL12250669 0.81 HDAC7 (0.34)
SCHEMBL7802720 0.81 HDAC7 (0.34)
SCHEMBL13631881 0.80 TGFBR1 (0.31)
SCHEMBL22872306 0.80 CA1 (0.32)
SCHEMBL10061083 0.80 CA1 (0.32)
SCHEMBL13227959 0.80 TGFBR1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7312211-B2 Pryanone compounds useful as reversible inhibitors of cysteine proteases BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. 2007-12-25 US disclosed