Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.40 |
| ▸ | CCND3 | P30281 | 1/20 | 0.40 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2886038 | 0.80 | KMT2A (0.43) | MEN1KMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL2884375 | 0.80 | KMT2A (0.51) | MEN1KMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL2880756 | 0.80 | MEN1 (0.43) | MEN1KMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL2884450 | 0.78 | MEN1 (0.46) | MEN1KMT2AALDH1A1KDM4EHTR6 | |
| SCHEMBL2885252 | 0.77 | ALDH1A1 (0.53) | MEN1KMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL2880658 | 0.76 | KMT2A (0.46) | MEN1KMT2AHTR6AGTR1MAPT | |
| SCHEMBL2886799 | 0.75 | ALDH1A1 (0.45) | MEN1KMT2ASMN1; SMN2ALDH1A1HTR6 | |
| SCHEMBL2885337 | 0.74 | MEN1 (0.43) | MEN1KMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL2885993 | 0.74 | KMT2A (0.43) | MEN1KMT2ALMNAALDH1A1KDM4E | |
| SCHEMBL2885267 | 0.74 | KMT2A (0.45) | MEN1KMT2ALMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007149557-A1 | FUSED [d]PYRIDAZIN-7-ONES | CEPHALON, INC. (US) | 2007-12-27 | — | — | WO | disclosed |