Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 7/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14347350 | 0.88 | SMN1; SMN2 (0.42) | CHRM3MEN1KMT2ACHRNA7HTR3E | |
| SCHEMBL14347502 | 0.83 | KMT2A (0.59) | CHRM3MEN1KMT2ASCN1ASCN2A | |
| SCHEMBL14374741 | 0.79 | ATM (0.41) | CHRM3MEN1KMT2AAPOBEC3AAPOBEC3G | |
| SCHEMBL14347349 | 0.74 | TSHR (0.47) | GAAMAPTRAB9ALMNAELANE | |
| SCHEMBL14347346 | 0.70 | BCL9 (0.39) | CHRM3CHRNA7GAARAB9ALMNA | |
| SCHEMBL14347342 | 0.70 | MEN1 (0.44) | MEN1KMT2AGAAMAPTNPC1 | |
| SCHEMBL14347383 | 0.70 | PDCD1 (0.42) | MEN1KMT2AGAAMAPTNPC1 | |
| SCHEMBL14347320 | 0.69 | MAPK1 (0.41) | KMT2AGAAMAPTLMNASCN1A | |
| SCHEMBL14347338 | 0.67 | ALDH1A1 (0.45) | MEN1KMT2AMAPTRAB9ALMNA | |
| SCHEMBL14347526 | 0.67 | TSHR (0.45) | KMT2AMAPTLMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7312211-B2 | Pryanone compounds useful as reversible inhibitors of cysteine proteases | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2007-12-25 | — | — | US | disclosed |